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혁신신약전공

이준석 부교수

Junseok Lee

위치첨단융합학부 18동 420호
연락처02-880-8466
이메일junseoklee@snu.ac.kr
학위박사 / 화학과, New York University
분야생화학, 유기화학
학력
– 박사: New York University, Organic Chemistry, USA(2009)
– 학사: POSTECH, Chemistry Korea(2005)
주요 경력
– 2025 ~ 현재: 서울대학교 첨단융합학부 부교수(자연과학대학 화학부 겸무) – 2021 ~ 2025: 고려대학교 의과대학 부교수 (2021 – 2025)
– 2013 ~ 2021: 한국과학기술연구원-UST 조교수/부교수 (2013 – 2021)
– 2010 ~ 2021: 한국과학기술연구원 책임연구원/선임연구원/연구원
최근 연구 성과
– “Chemical proteomics for a comprehensive understanding of functional activity and the interactome.”, Kozoriz, K; Lee, J. S.* Chem. Soc. Rev., 2025, 54, 6186-6207.
– “Disaggregation-Activated pan-COX Imaging Agents for Human Soft Tissue Sarcoma” Hong, K. T.; Park S. B.; Murale, D. P.; Lee, J. H.; Hwang, J.; Jang, W. Y.*; Lee, J. S.* Angew. Chem. Int. Ed., 2024, 63(24), e202405525
– “Multifunctional Photo-Cross-linking Probes: From Target Protein Searching to Imaging Applications” Kozoriz, K; Shkel, O; Hong, K. T.; Kim, D. H.; Kim, Y. K.; Lee, J. S.* Acc. Chem. Res., 2023, 56(1), 25-36.
– “Orthogonally-Tunable and ER-Targeting Fluorophores Detect Avian Influenza Virus Early Infection” Kang, T.; Haque, M. M.; Lee, B.; Hong, K. T.; Hong, S. C.; Kim, Y.; Lee, J.; Lee, J. S.*; Lee, D.* Nat. Commun., 2022, 13. 5841.
– “Targeted Degradation of Transcription Co-activator SRC-1 through the N-Degron Pathway” Lee, Y.; Heo, J.; Jeong, H.; Hong, K. T.; Kwon, D. H.; Shin, M. H.; Oh, M.; Sable, G. A.; Ahn, G. O; Lee, J. S.*; Song, H. K. *; Lim, H. S.* Angew. Chem. Int. Ed., 2020, 59,17548-17555.
– “Discrimination of Avian Influenza Virus using Host-cell Infection Fingerprinting by Sulfinate-based Fluorescence Superoxide Probe” Hong, S. C.; Murale, D. P.; Jang, S. Y.; Haque, M. M.; Seo, M.; Lee, S.; Woo, D. H.; Kwon,J.; Song, C. S.; Kim, Y. K.; Lee, J. S.* Angew. Chem. Int. Ed., 2018, 57, 9716-9721.
Education
– Ph.D. Organic Chemistry, New York University, USA, 2009
– B.S. Chemistry, POSTECH, Korea, 2005
Professional Experience
– Associate Professor, School of Transdisplinary Innivation and Department of Chemistry, Seoul National University, 2025 – current
– Associate Professor, Korea University College of Medicine, 2021-2025
– Assistant/Associate Professor, KIST School UST, 2013-2021
– Principal/Senior/Researcher, Korea Institute of Science and Technology, 2010-2021
Recent Research Achievements
– “Chemical proteomics for a comprehensive understanding of functional activity and the interactome.”, Kozoriz, K; Lee, J. S.* Chem. Soc. Rev., 2025, 54, 6186-6207.
– “Disaggregation-Activated pan-COX Imaging Agents for Human Soft Tissue Sarcoma” Hong, K. T.; Park S. B.; Murale, D. P.; Lee, J. H.; Hwang, J.; Jang, W. Y.*; Lee, J. S.* Angew. Chem. Int. Ed., 2024, 63(24), e202405525
– “Multifunctional Photo-Cross-linking Probes: From Target Protein Searching to Imaging Applications” Kozoriz, K; Shkel, O; Hong, K. T.; Kim, D. H.; Kim, Y. K.; Lee, J. S.* Acc. Chem. Res., 2023, 56(1), 25-36.
– “Orthogonally-Tunable and ER-Targeting Fluorophores Detect Avian Influenza Virus Early Infection” Kang, T.; Haque, M. M.; Lee, B.; Hong, K. T.; Hong, S. C.; Kim, Y.; Lee, J.; Lee, J. S.*; Lee, D.* Nat. Commun., 2022, 13. 5841.
– “Targeted Degradation of Transcription Co-activator SRC-1 through the N-Degron Pathway” Lee, Y.; Heo, J.; Jeong, H.; Hong, K. T.; Kwon, D. H.; Shin, M. H.; Oh, M.; Sable, G. A.; Ahn, G. O; Lee, J. S.*; Song, H. K. *; Lim, H. S.* Angew. Chem. Int. Ed., 2020, 59,17548-17555.
– “Discrimination of Avian Influenza Virus using Host-cell Infection Fingerprinting by Sulfinate-based Fluorescence Superoxide Probe” Hong, S. C.; Murale, D. P.; Jang, S. Y.; Haque, M. M.; Seo, M.; Lee, S.; Woo, D. H.; Kwon,J.; Song, C. S.; Kim, Y. K.; Lee, J. S.* Angew. Chem. Int. Ed., 2018, 57, 9716-9721.